Protein

UniProt accession
A0A059T7Q7 [UniProt]
Protein name
N-acetylmuramoyl-L-alanine amidase
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWQVLFGYNLKGVGAKDIPSANNFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSVQSPTQTPKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPKFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYVSGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFISTSCPHRSSVLHTGFDPVTRGLIPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTSVLLQDNHVWLEYEWQGNLYYIPIRSWDGTPPPNQILGDLWGEIS
Physico‐chemical
properties
protein length:481 AA
molecular weight:53945,00000 Da
isoelectric point:8,47928
aromaticity:0,12682
hydropathy:-0,50416

Domains

Domains [InterPro]
IPR036505
192–330
IPR036505 IPR003646 IPR007921
IPR003646
395–460
IPR003646 IPR038765 IPR002502
IPR007921
7–148
IPR007921 IPR002502
IPR036505
181–362
IPR036505
IPR002502
199–324
IPR002502
Protein sequence: A0A059T7Q7
1 481
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage DW2
[NCBI] 		1464127 Phietavirus >
Host Staphylococcus aureus
[NCBI] 		1280 Bacteria > Firmicutes > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AHL18470.1 [NCBI]
Genbank nucleotide accession
KJ140076 [NCBI]
CDS location
range 39558 -> 41003
strand +
CDS
ATGCAAGCAAAACTAACTAAAAAAGAGTTTATAGAGTGGTTGAAAACATCTGAGGGAAAACAATATAATGCGGACGGATGGTATGGGTTTCAATGCTTCGATTATGCCAATGCAGGTTGGCAAGTCTTATTTGGCTACAACTTAAAAGGTGTAGGTGCCAAAGACATACCAAGTGCGAATAATTTTGACGGACTAGCTACTGTATACCAAAATACACCAGACTTCTTAGCGCAACCTGGCGACATGGTTGTGTTCGGTAGCAACTACGGTGCTGGATATGGTCACGTAGCATGGGTAATTGAAGCAACTTTAGATTATATCATTGTATATGAGCAGAATTGGCTCGGCGGTGGCTGGACAGACGGCGTACAACAACCTGGCTCTGGTTGGGAAAAAGTTACAAGACGCCAACACGCTTACGACTTCCCTATGTGGTTTATCCGTCCTAACTTCAAAAGCGAAACAGCTCCACGATCAGTACAATCTCCTACGCAAACACCTAAAAAAGAAACGGCTAAGCCACAACCTAAAGCGGTAGAACTTAAAATCATCAAAGATGTGGTTAAAGGTTATGACTTGCCTAAGCGTGGTAGTAACCCTAAGTTTATAGTTATTCACAACGACGCAGGAAGCAAAGGAGCAACAGCAGAAGCATATCGTAATGGATTAGTTAACGCGCCATTATCGAGACTAGAGGCAGGTATTGCGCATAGTTACGTATCAGGTAACACAGTTTGGCAAGCCTTAGATGAATCTCAAGTAGGTTGGCATACAGCGAATCAAATAGGTAATAAATATGGTTACGGTATTGAAGTGTGTCAATCAATGGGCGCAGATAACGCGACATTCTTAAAAAATGAACAGGCAACTTTCCAAGAATGCGCTAGATTGTTAAAAAAATGGGGATTACCAGCAAACAGAAATACAATCAGATTGCACAACGAATTCATTTCAACATCATGCCCACATAGAAGTTCAGTATTGCACACTGGCTTTGACCCAGTGACTCGCGGGCTAATACCAGAAGACAAACGTTTACAACTTAAAGACTACTTCATCAAACAGATTAGGGCGTACATGGATGGTAAAATACCAGTTGCCACTGTCTCTAATGAGTCAAGCGCTTCAAGTAATACAGTTAAACCAGTTGCGAGTGCATGGAAACGAAATAAATATGGCACTTACTACATGGAAGAGAGCGCTAGATTCACAAACGGCAATCAACCAATCACAGTAAGAAAAGTTGGACCATTCTTATCATGTCCAGTGGGTTATCAGTTCCAACCGGGTGGATATTGTGATTATACTAGCGTGTTACTCCAAGATAACCACGTATGGCTTGAATACGAATGGCAAGGAAATCTCTACTATATTCCTATTCGTTCATGGGACGGAACACCACCACCTAATCAGATATTAGGTGACTTATGGGGAGAAATCAGTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell Biological process Inferred from Electronic Annotation (InterPro)
GO:0006508 proteolysis Biological process Inferred from Electronic Annotation (InterPro)
GO:0008233 peptidase activity Molecular function Inferred from Electronic Annotation (InterPro)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0046872 metal ion binding Molecular function Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 N-acetylmuramoyl-L-alanine amidase residues in certain cell-wall glycopeptides
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available.