Protein

UniProt accession
A0A0M4S5S1 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MEMSSNGINMLKGFEGCRLAAYQDSVGVWTIGYGWTQPVNDVPVGKGMTITQETADSLLCSGLVQYEKGVTGLVKVTINQNQFDALVDFAYNLGVKALEGSTLLKKLNAGDYAGAAAEFPKWNKAGGKVLPGLVKRREAERTLFLA
Physico‐chemical
properties
protein length:146 AA
molecular weight:15694,00000 Da
isoelectric point:7,69557
aromaticity:0,08904
hydropathy:-0,05205

Domains

Domains [InterPro]
IPR033907
7–145
IPR033907
IPR023347
2–146
IPR023347
IPR002196
12–140
IPR002196
IPR051018
2–145
IPR051018
IPR034690
1–146
IPR034690
IPR023346
2–145
IPR023346
Protein sequence: A0A0M4S5S1
1 146
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Salmonella phage SEN4
[NCBI] 		1647465 Peduoviridae > Senquatrovirus > Senquatrovirus SEN4
Host Salmonella enterica subsp. salamae
[NCBI] 		59202 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Salmonella

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ALF02298.1 [NCBI]
Genbank nucleotide accession
KT630645 [NCBI]
CDS location
range 7090 -> 7530
strand +
CDS
GTGGAGATGAGTAGTAACGGCATCAACATGCTGAAAGGCTTTGAAGGGTGCAGGCTGGCCGCTTATCAGGATTCTGTAGGCGTCTGGACGATCGGTTATGGATGGACTCAACCTGTCAACGACGTGCCGGTTGGTAAGGGCATGACTATTACGCAGGAAACTGCCGATAGCCTGTTGTGTAGCGGTCTGGTGCAGTATGAAAAAGGCGTTACGGGGCTGGTTAAAGTCACCATCAATCAAAATCAGTTCGATGCGCTGGTTGATTTTGCCTACAACCTGGGCGTAAAGGCGCTGGAAGGTTCCACACTGCTGAAAAAGCTGAATGCTGGCGATTACGCCGGGGCTGCGGCTGAGTTTCCAAAATGGAATAAAGCAGGCGGCAAGGTGTTGCCGGGGCTGGTTAAACGTCGGGAAGCCGAGCGCACGTTATTTCTGGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi0006ce3cb9_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A