Protein

UniProt accession
A0A0P0M6C8 [UniProt]
Protein name
Peptidoglycan transglycosylase gp16
PhaLP type
VAL

evidence: Protein name annotation

probability: 99 % (predicted by ML model)

Protein sequence
MSYDKSKPSDYDGLFQKASDSHGVSYDLLRKLAFNESSFNPNAKSKTGPKGIMQFTTGTARGLGLNVADVGIDDPMDDRYKPELAIDAAARHLSDLVRKYNGDELKAALAYNQGEGRTGAPQMEAYDKGDFAAISEEGRNYMRKLMDVANSPRKGELEAFGGITPKGKGIPASDAFAGMSKATKVSQDLPDSTGFNVTGKEQAAPAVPYAKDFWEKTGTTIDEFEARSTFFGFKDATKAELHNSTLGVAFRAGRADNGWDVFKDVLTPTRWNSYQPTAEDLDKLRNSGLPPSYYSVVTGGDGENWDDLIKMAKDNYEMDRKAADAGLGAKLSAGVIGAGVDPLSYIPLVGVAGKGIKVVNKALVVGTQGAALSMASEAIRTSVAGGDAHYADAALGGLIFGAGMSALSDAVSAGLRRAGSKTDGLNEFAGPAMRLEARESAYNAGGTDTSRLPSETQVFDGEHVGVRYAEHPSEQGSVVLENGSILMDTNPANPKTIKEFTEIDPERAAPGVKLGGFTEIGLKTLSSDTPEIRSIASDLVRSPTGMASGSHGKFGATSSDIHERLHGTDQKTYNELYGAVREAMNDPEFSMGEAKMSREGIRQEIYKRAALAIERPELQAGLTKGERKVMDLMKRHFDTKRELMENPAIFGNFNATSIFPGSRHKGTYVPNVYDRSVKQLMAQQLGAEGLQEAIAKSWLTSYHSRPEVKSRVDEYLMELNGYKSAAEVTPEVVQKHAMDKAYGISHTDQFNASFVIDDNITGLVGIENNSFLEARNMFDSDMATTLPDGSTFSVNDLRDFDMFRIMPAYDRRINGDIAIMGGTGKTTKELKDAIMALDKKSEGNGKMKGEVEALKDTVKILTGRARRNNDTAFETMIRGLNDLTFFAKNFYMGPQNVTEIAGMLAKGNVKAMLHGIPTVRDLAFKKGPLSGKELKDIHGALFGKELDQLIRPGRADIVQRMREASDTSVVMSNIVGTLKYGTQELSARSPWTKMLNGTANYLLDAARQGVLGDVAGAALGGKGSKFGTDAFLKSASISKEQWAGIKSLFRDHAVRDASGQFTIKDKKAFSQDPRSMDLWRLADKVADETMLRPHKVSSQDSHAYGAGVKMFMQFKNFTIKSLNSKFVRSYYEATKNSRGIDMALTHILSLGIAGGYFAMQAHVKALGLPDHQQKDYLKKALNPTMLGYAALTRSSHLGAPFSIPSMIAGAAGFNEANMLRSTILPKEEPKRDKGKPMTSREAASNFMGSLGGQVPAIGWVGSAVSSVYNAAGVLTAPNKPTERDYMTGLMNSTRELVPNDPLTQQLIMKIYEANGVHIKEDKRPN
Physico‐chemical
properties
protein length:1325 AA
molecular weight:143518,00000 Da
isoelectric point:7,69835
aromaticity:0,07547
hydropathy:-0,42913

Domains

Domains [InterPro]
IPR000189
32–60
IPR000189
IPR023346
5–151
IPR023346
IPR008258
14–130
IPR008258
IPR038994
1–1314
IPR038994
Protein sequence: A0A0P0M6C8
1 1325
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Yersinia phage vB_YenP_AP10
[NCBI] 		1735591 Autographiviridae > Apdecimavirus > Apdecimavirus AP10
Host Yersinia enterocolitica
[NCBI] 		630 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Yersinia

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ALK86968.1 [NCBI]
Genbank nucleotide accession
KT852574 [NCBI]
CDS location
range 29593 -> 33570
strand +
CDS
ATGAGTTACGATAAATCAAAACCTAGCGACTACGATGGGTTGTTCCAGAAGGCATCTGACTCTCATGGGGTCAGCTATGACCTGCTTCGTAAGTTAGCCTTCAACGAGTCAAGTTTTAACCCTAACGCCAAGTCCAAGACTGGTCCTAAGGGAATCATGCAGTTCACCACTGGGACCGCTCGCGGTCTCGGTCTTAACGTTGCAGACGTGGGTATTGATGACCCAATGGATGACCGCTACAAGCCTGAACTGGCTATTGACGCTGCGGCCCGCCACCTGTCTGACCTTGTGCGCAAGTACAATGGTGACGAACTCAAAGCAGCCCTAGCGTACAACCAAGGGGAAGGCCGTACTGGCGCTCCTCAGATGGAAGCATACGACAAGGGCGACTTCGCGGCTATCTCAGAGGAAGGTCGTAACTACATGCGTAAACTTATGGACGTAGCCAATAGCCCTCGTAAGGGCGAACTGGAAGCGTTCGGCGGTATTACCCCAAAGGGTAAGGGCATCCCTGCGTCTGACGCTTTCGCTGGTATGTCCAAGGCAACCAAAGTGTCTCAGGACCTACCTGACTCCACAGGGTTCAATGTCACAGGTAAAGAGCAGGCAGCGCCAGCCGTCCCTTACGCTAAGGACTTCTGGGAGAAGACCGGGACGACTATTGATGAGTTTGAAGCTCGCTCCACGTTCTTTGGCTTTAAGGATGCCACCAAGGCTGAGTTACATAACTCAACGCTGGGTGTGGCCTTCCGTGCTGGACGTGCAGACAACGGCTGGGATGTCTTCAAGGATGTCTTAACGCCGACCCGCTGGAACTCCTATCAGCCAACCGCTGAGGACTTGGACAAGCTGCGTAACAGTGGCCTGCCTCCGAGTTATTACTCTGTGGTGACTGGTGGTGACGGTGAGAACTGGGACGACCTGATTAAGATGGCTAAAGACAACTACGAGATGGACCGTAAGGCCGCTGACGCTGGACTGGGTGCCAAACTGAGCGCTGGTGTCATCGGTGCCGGTGTGGACCCCCTGAGTTACATCCCATTGGTGGGTGTAGCTGGCAAGGGCATCAAGGTGGTCAACAAGGCTCTTGTAGTCGGCACCCAAGGTGCTGCACTGAGCATGGCCTCAGAGGCTATCCGTACCTCTGTGGCTGGTGGTGATGCTCACTACGCTGATGCTGCCCTTGGTGGCCTCATCTTTGGTGCTGGTATGTCTGCCCTGAGTGATGCTGTGAGTGCTGGCCTTCGCCGAGCTGGAAGCAAGACCGATGGACTCAATGAGTTCGCTGGTCCAGCTATGCGATTAGAAGCCCGTGAGTCAGCCTACAACGCTGGCGGTACGGACACTTCACGTCTACCTAGCGAGACCCAAGTGTTTGACGGTGAGCACGTTGGCGTGAGGTACGCTGAGCATCCTAGCGAGCAAGGCTCTGTGGTGCTGGAGAATGGCTCTATCCTGATGGACACCAACCCTGCTAACCCTAAGACCATCAAGGAGTTCACTGAGATTGACCCTGAGCGTGCAGCGCCCGGAGTTAAACTTGGTGGGTTTACTGAGATTGGCCTTAAGACGTTAAGCTCGGATACACCAGAAATCCGTAGCATCGCGTCAGACCTAGTGCGTTCTCCTACTGGCATGGCCTCAGGGTCACACGGTAAGTTCGGCGCTACGTCCTCTGACATCCACGAGCGTCTCCACGGTACTGACCAGAAGACTTACAATGAGTTGTATGGCGCTGTCCGTGAAGCGATGAATGACCCAGAGTTCTCTATGGGCGAAGCCAAGATGTCCCGTGAAGGTATCCGTCAGGAAATCTACAAACGTGCTGCCCTAGCGATTGAGCGCCCAGAGTTACAGGCTGGCCTGACCAAGGGTGAACGTAAGGTGATGGACCTGATGAAACGCCACTTCGACACCAAGCGCGAACTGATGGAGAACCCAGCTATCTTCGGTAACTTCAACGCCACCAGCATCTTCCCCGGCAGTCGTCACAAAGGGACCTATGTGCCTAACGTATATGACCGCTCCGTGAAGCAACTGATGGCGCAGCAGCTTGGGGCCGAGGGTCTACAGGAAGCAATCGCTAAGTCTTGGCTGACGAGCTACCATAGCCGTCCTGAGGTTAAATCTCGTGTCGATGAGTACCTGATGGAACTGAACGGCTACAAGTCAGCCGCTGAGGTGACACCTGAGGTCGTCCAGAAGCACGCGATGGATAAGGCTTATGGTATCAGTCACACAGACCAGTTCAACGCTTCGTTTGTCATTGATGACAACATTACTGGTCTGGTTGGGATTGAGAACAACTCATTCCTTGAAGCTCGTAACATGTTCGACTCAGACATGGCGACTACCTTACCGGATGGCTCTACGTTCTCAGTGAACGACCTCCGCGACTTCGACATGTTCCGCATCATGCCTGCATATGACCGCCGCATCAACGGTGACATCGCTATCATGGGTGGCACAGGGAAGACGACTAAGGAACTTAAAGATGCCATCATGGCACTAGACAAGAAGTCTGAGGGTAACGGTAAGATGAAAGGCGAGGTGGAAGCACTCAAGGATACCGTGAAGATTCTGACTGGACGTGCTCGTCGTAACAACGACACAGCGTTCGAGACGATGATTCGTGGACTGAATGACCTAACGTTCTTCGCTAAGAACTTCTACATGGGCCCTCAGAACGTCACTGAGATTGCTGGGATGTTGGCTAAGGGTAACGTCAAGGCGATGCTCCACGGGATTCCTACAGTTCGTGACCTTGCATTCAAGAAGGGCCCACTTAGCGGTAAGGAACTCAAGGACATCCACGGTGCGTTGTTCGGTAAGGAACTGGACCAGCTTATTCGTCCGGGCCGTGCTGACATTGTGCAACGTATGCGTGAAGCCTCTGATACCAGTGTCGTGATGTCTAACATTGTGGGGACCTTGAAGTATGGCACACAGGAACTCTCTGCGCGTTCTCCGTGGACCAAGATGTTGAACGGTACAGCCAACTACCTTCTGGATGCAGCCCGTCAGGGCGTGCTTGGAGATGTGGCAGGTGCAGCCTTAGGTGGCAAAGGGTCGAAGTTCGGCACCGATGCTTTCCTGAAATCAGCGAGTATCTCTAAGGAACAGTGGGCTGGTATCAAGTCCCTCTTCCGAGACCACGCTGTGCGAGATGCCTCAGGGCAGTTCACCATCAAGGACAAGAAGGCGTTCAGTCAGGACCCTCGCAGTATGGACCTGTGGCGATTAGCCGATAAGGTGGCTGATGAGACCATGCTTCGCCCGCACAAGGTGTCCTCTCAGGATTCCCATGCGTATGGTGCTGGCGTGAAGATGTTCATGCAGTTTAAGAACTTCACCATCAAGTCACTGAACTCGAAGTTCGTTCGGTCTTACTACGAGGCCACTAAGAACTCTCGCGGTATTGACATGGCGTTGACCCACATCCTTTCTCTGGGAATCGCTGGTGGCTACTTCGCTATGCAGGCCCATGTGAAGGCTCTTGGTCTCCCGGACCATCAACAGAAGGACTACCTCAAGAAGGCGCTTAACCCGACCATGTTGGGCTACGCCGCGTTGACCCGTAGTTCTCATCTGGGTGCTCCATTCAGTATCCCTTCCATGATTGCTGGTGCTGCTGGATTCAATGAGGCCAACATGCTCCGCTCTACGATTCTACCTAAGGAAGAACCTAAGCGCGATAAGGGCAAGCCGATGACATCCCGTGAGGCCGCATCTAACTTCATGGGCAGTCTTGGCGGTCAGGTCCCGGCTATTGGTTGGGTTGGCTCTGCGGTCTCCTCAGTGTATAACGCTGCGGGTGTTCTCACTGCACCTAACAAGCCAACTGAGCGTGACTACATGACTGGGCTTATGAACTCTACCCGTGAGTTGGTTCCTAACGACCCACTGACGCAGCAGTTAATCATGAAGATTTATGAGGCCAATGGTGTCCACATCAAGGAAGACAAGCGTCCGAATTAA

Gene Ontology

Description Category Evidence (source)
GO:0000270 peptidoglycan metabolic process Biological process Inferred from Electronic Annotation (UniProt)
GO:0008933 peptidoglycan lytic transglycosylase activity Molecular function Inferred from Electronic Annotation (TreeGrafter)
GO:0016020 membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0016787 hydrolase activity Molecular function Inferred from Electronic Annotation (InterPro)
GO:0020002 host cell plasma membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044423 virion component Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)
GO:0099002 symbiont genome ejection through host cell envelope, short tail mechanism Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
4.2.2.n1 peptidoglycan lytic exotransglycosylase
aka exomuramidase; murein lyase F 		in the MurNAc residue
Lyases
Carbon-oxygen lyases
Acting on polysaccharides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04121

Tertiary structure

PDB ID: upi000706ce69_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A