Protein

UniProt accession
A0A193GZK4 [UniProt]
Protein name
Pre-baseplate central spike protein
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MKLGGNLHSPFFDGVVENVDDPRGLGRVQVRVFGQHPAQKQKSDAIGVPVEDLPWMMPIQDIRSAAISGVGFSPTGITRGSFVVGYWRDKWHQDGMIIGTVAGEYVEQPDTQKGFCDPMGEYPRYVGNDVNSLALGGLKGKGSSSVIIRDSNTSIAVNPDDRPLDEIPEDNRPDTGGFTIEKMLKQDEGIRTRWYTDSEGYPTIGIGHLLIREKTRDTAKINAAISKAVGREVTNGTITAEEVSTLFAQDLAKVRSDIQRTANVREVYVNLNRPRQMAIENMSFQMGVGGVAKFTNTLKAMKNEDWQAAYNGLRNSLWASQTPGRSSRVSKIVLTGNLESYGVQVPDPEGRSLSAAYAAYNGATLLAASPEDPFTPGDTRVMFEEPASSYNAEYPYNMVFESRSGHIQEFDDTPGYERYNRVHPAGSYEEIRPDGTRVVKIVGDDYQIVMQGRKLNVKGNLQVVIEGDAFIYNMGNVQQTVDGNVTEFVRGNVQQTVEGEYVGLIKGNAELTVNKDATVNVDQNLTANVKQNATVAVTEDATVTAKNAKIEIEETMDIGAKDINIKATNNTFIDSGALTKITGGTVQVG
Physico‐chemical
properties
protein length:589 AA
molecular weight:64314,00000 Da
isoelectric point:5,06625
aromaticity:0,07301
hydropathy:-0,44058

Domains

Domains [InterPro]
IPR052619
179–340
IPR052619 IPR009590 IPR010609
IPR002196
185–314
IPR002196
IPR046397
4–589
IPR046397
IPR023347
178–344
IPR023347
IPR023346
132–345
IPR023346
IPR001165
181–200
IPR001165
Protein sequence: A0A193GZK4
1 589
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage phT4A
[NCBI] 		1852638 Straboviridae > Slopekvirus > Slopekvirus pht4A
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ANN86451.1 [NCBI]
Genbank nucleotide accession
KX130727 [NCBI]
CDS location
range 99514 -> 101283
strand +
CDS
ATGAAATTAGGCGGAAATTTACACTCCCCTTTCTTTGATGGGGTGGTTGAAAACGTTGATGATCCGCGCGGGTTGGGCCGTGTTCAAGTCCGTGTATTTGGACAACACCCAGCCCAAAAACAAAAATCCGATGCAATCGGTGTTCCTGTTGAAGATTTACCCTGGATGATGCCTATTCAGGATATTAGAAGCGCTGCGATCTCTGGTGTGGGCTTCTCTCCAACTGGTATCACTCGCGGATCCTTTGTTGTTGGTTATTGGCGTGACAAATGGCACCAAGATGGTATGATAATTGGTACTGTCGCTGGTGAATATGTCGAACAACCAGACACACAGAAAGGTTTTTGCGATCCTATGGGTGAATACCCTCGCTATGTTGGTAACGATGTTAACTCCCTTGCTTTAGGTGGTTTGAAAGGCAAAGGATCATCAAGTGTCATCATTCGTGATTCAAACACAAGCATAGCAGTAAACCCAGACGATCGCCCACTGGATGAGATACCAGAAGATAACCGCCCTGATACGGGTGGATTTACGATCGAAAAGATGCTCAAGCAGGATGAGGGGATCCGTACACGATGGTATACAGACAGTGAAGGATATCCGACAATCGGGATCGGGCATTTGCTTATCCGCGAAAAGACTCGCGACACTGCAAAAATTAACGCTGCGATCAGTAAAGCGGTAGGTCGAGAAGTAACAAACGGAACAATCACGGCAGAAGAGGTATCAACCTTATTTGCTCAAGATTTAGCCAAAGTAAGATCTGATATTCAGAGAACCGCTAACGTCCGTGAAGTGTATGTGAACCTCAACCGTCCTCGTCAAATGGCGATCGAAAACATGTCGTTTCAAATGGGCGTCGGTGGTGTTGCTAAATTCACCAATACCCTGAAAGCGATGAAAAATGAAGATTGGCAAGCGGCTTATAATGGTCTTCGAAATTCACTGTGGGCTAGTCAAACTCCAGGCCGTTCTTCTCGCGTGTCTAAAATAGTCCTCACGGGCAACCTTGAATCATATGGGGTACAAGTACCAGATCCGGAAGGGCGCTCTCTGAGTGCTGCTTACGCTGCGTATAACGGTGCTACATTGCTGGCGGCTAGTCCGGAAGATCCTTTTACTCCTGGTGATACCCGTGTGATGTTTGAAGAACCAGCATCATCTTATAATGCTGAATATCCGTACAATATGGTTTTTGAATCGAGATCCGGACACATTCAGGAATTCGATGATACCCCAGGATACGAACGATATAACCGTGTTCACCCAGCAGGGAGTTACGAAGAAATTCGCCCGGATGGAACCCGCGTTGTTAAAATCGTAGGGGATGATTATCAAATTGTGATGCAGGGCCGGAAACTCAACGTTAAAGGCAACTTGCAGGTAGTTATTGAAGGCGACGCATTCATTTACAACATGGGTAACGTTCAACAAACGGTTGATGGTAACGTAACTGAGTTTGTTCGTGGCAACGTTCAACAAACGGTTGAAGGTGAGTACGTTGGCCTGATTAAAGGCAATGCTGAACTAACTGTAAACAAAGATGCAACAGTTAACGTTGATCAGAATCTTACCGCAAATGTGAAACAGAATGCAACCGTGGCTGTAACAGAAGACGCAACGGTCACTGCAAAAAATGCGAAAATTGAGATTGAAGAAACGATGGATATCGGTGCTAAAGATATCAATATCAAAGCAACGAATAACACGTTTATTGATTCTGGCGCATTAACAAAAATCACTGGCGGCACCGTCCAAGTGGGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0098003 viral tail assembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0098025 virus tail, baseplate Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

PDB ID: upi0006bc1018_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A