Protein

UniProt accession
A0A219YHA3 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEHGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQSLRSLLVELKVQYAGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
Physico‐chemical
properties
protein length:151 AA
molecular weight:16837,00000 Da
isoelectric point:8,46884
aromaticity:0,07947
hydropathy:-0,39007

Domains

Domains [InterPro]
IPR002502
15–132
IPR002502
IPR015510
11–133
IPR015510
IPR002502
1–151
IPR002502
IPR036505
7–151
IPR036505
IPR006619
1–124
IPR006619
IPR002502
11–132
IPR002502
IPR036505
11–146
IPR036505
IPR034689
1–149
IPR034689
Protein sequence: A0A219YHA3
1 151
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage K5-2 (Bacteriophage K5-2)
[NCBI] 		1932361 Autographiviridae > Przondovirus > Przondovirus K52
Host Klebsiella
[NCBI] 		570 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae >

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
APZ82782.1 [NCBI]
Genbank nucleotide accession
KY389315 [NCBI]
CDS location
range 10819 -> 11274
strand +
CDS
ATGGCCAAGGTTCAATTCACTAAGCGACAGGAGACCTCTCAGATTTTCGTTCACTGCTCGGCCACCAAGGCAACCATGGACGTAGGTGTCCGTGAGATTCGCCAGTGGCACAAAGAGCATGGCTGGCTGGACGTTGGGTATCACTTCATCATCCGTCGTGACGGTACCGTTGAGGCGGGCCGCGACCAAGACGCTGTGGGTTCCCACGTCAAGGGATACAACTCGACTTCTGTCGGTGTGTGTCTGGTAGGTGGTATCGACGCCAAGGGTAACCCTGAGGCAAACTTCACGCCAGCCCAGATGCAGTCGCTGCGTTCACTGCTGGTAGAACTGAAGGTGCAATACGCTGGGGCCGTGCTGATGGCACACCACGATGTAGCACCTAAAGCCTGCCCGAGCTTCGACCTGAAGCGCTGGTGGGAGAAGAACGAACTGGTCACTTCTGACCGTGGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008270 zinc ion binding Molecular function Inferred from Electronic Annotation (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0032897 negative regulation of viral transcription Biological process Inferred from Electronic Annotation (InterPro)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 N-acetylmuramoyl-L-alanine amidase residues in certain cell-wall glycopeptides
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04111

Tertiary structure

PDB ID: upi000b5fb04b_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A