Protein

UniProt accession
A0A219YHC1 [UniProt]
Protein name
Peptidoglycan transglycosylase gp16
PhaLP type
VAL

evidence: Protein name annotation

probability: 99 % (predicted by ML model)

Protein sequence
MSYDKSKPSDYDGIFQKAADSHGVSYDLLRKLSFNESSFNPKAISKTGPKGIMQFTRNTARAMGLNVTDGDDDGRYNPELAIDAGAKLLASLVKKYNGDELKAALAYNQGEGPSGAPQLQAYDKGDFGSISEEGRNYMRKLLDVAKSPNSGALEAFGGVTPKGKGIPAEDAFKGIAKAGKVGTELPESHGFDIEGVAQEAPNTPYAKDFWEKTGTTLDEYNARSTFFGFGDAAEAQIQNSTLGVAFRAARADDGYDVFKDTMTPTRWNSYVPSKEDLQKLRDSGLPPSYYGVVTGGDGENWDALIKLAKDNFEADQRAAEAGTGAKLAAGIVGAGVDPLSYVPLVGVAGKGLKVVNKALRVGAQAGALSVASEGIRTSVAGGEAHYADAALGGLLFGAGMSALSDAVAAGIRKARGVESVNEFAGPALRMEARETAINTGGHDTSTLPPENFSFEQDHRGVPFADHPTEEGAVVLANGSILSDTNPLNPRTQRDFAEIDPERAAPGIKLGGFTEIGLKTLGSKDAGVRAIAQDLVRSPTGMQSGSSGKFGATASDIHERLHATDQRMYNQLYDAVDRAMKDPEFSVGEQKMSRRAIRQEVYKRAALAIERPELQADLTKGEREVMDLLKEHFDTKRELMEQPGIFGNANAVSIFPGSRHKGTYVPNVYDRGAKELMMQKLGGPEGLQQAIAQSWLTSYRVRPEVKARVDEYLMELNGYKSVDQVTPEVVQKHAMDKAYGISHTEDFTASSVIDDNITGLVGIENNSFLEARNMFDSDLPVTLPDGSTFSVNDLRDFDMARIIPAYDRRVNGDISIMGGSGKTTQQLKDEIMALDKRAERKGQLKGEVEALKDTVKILTGRARRNHDTAFETAMRTLNDLAFFAKNFYMGPQNLTEIAGMLAKGNVKAMLHGIPTLRDLATRTSPVSGSELRELHGALFGKELDQLIRPGREDIVQRIREASDTSGAMASVIGTIKFGTQELSARSPWTKMLNGTANYILDTARQGVLGDVAGAALGGKGSKFGKENFLKAASISPEQWKGIKQLFVDHATRDANGQFTIKDKKAFSQDPRAMDLWRLADKVADETMLRPHKVSQQDSKAYGAGVKMAMQFKNFTIKSLNAKFIRSFYEGYKNNRAIDMALTHVLSLGIAGTYFAMQAHVKAYGLQESQRKDYLKKALNPTMLGYAALTRSSHTGAPLSIVSMMAGAAGFQDANMLRSTILPKEEQFQKKDGASKGRAESSNLAGNLGSQVPALGYVGNVIATAKNAYGVATAPNKPTERDYMTGLMNSTKELVPNDPLTQQLIMKIYEANGVTIKQQPKPN
Physico‐chemical
properties
protein length:1321 AA
molecular weight:142717,00000 Da
isoelectric point:7,08546
aromaticity:0,07267
hydropathy:-0,43460

Domains

Domains [InterPro]
IPR008258
15–125
IPR008258
IPR000189
32–60
IPR000189
IPR023346
5–146
IPR023346
IPR038994
1–1310
IPR038994
Protein sequence: A0A219YHC1
1 1321
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage K5-2 (Bacteriophage K5-2)
[NCBI] 		1932361 Autographiviridae > Przondovirus > Przondovirus K52
Host Klebsiella
[NCBI] 		570 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae >

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
APZ82803.1 [NCBI]
Genbank nucleotide accession
KY389315 [NCBI]
CDS location
range 29113 -> 33078
strand +
CDS
ATGAGCTACGATAAGTCCAAACCTAGCGATTACGATGGCATTTTCCAGAAGGCAGCAGACTCTCATGGGGTCTCCTATGACCTCCTGCGTAAGTTATCGTTTAACGAATCATCCTTCAACCCTAAGGCCATCTCTAAGACTGGCCCTAAGGGCATCATGCAGTTCACCCGCAACACGGCCCGCGCTATGGGCCTTAACGTGACCGATGGTGACGACGATGGGCGTTACAACCCAGAGTTAGCCATTGACGCTGGCGCTAAGCTGCTTGCGAGCCTCGTTAAGAAGTACAATGGGGATGAGCTGAAAGCAGCCCTAGCGTACAACCAAGGGGAAGGCCCATCGGGTGCACCTCAGCTTCAGGCTTACGATAAGGGCGACTTCGGGTCTATCTCCGAGGAAGGACGCAACTACATGCGCAAGCTGCTGGACGTGGCTAAGAGTCCCAACTCTGGCGCTCTGGAAGCGTTCGGCGGCGTCACCCCAAAGGGTAAAGGGATTCCCGCAGAGGATGCCTTCAAGGGCATCGCTAAGGCTGGAAAGGTTGGTACCGAACTGCCGGAGTCCCATGGGTTCGACATTGAGGGTGTAGCGCAGGAAGCGCCCAACACACCATACGCTAAGGACTTCTGGGAGAAGACCGGGACGACTCTCGATGAGTATAACGCTCGGTCCACCTTCTTCGGATTCGGGGATGCTGCTGAGGCTCAGATTCAGAACTCCACCTTGGGTGTGGCCTTCCGTGCTGCACGTGCTGACGATGGGTACGATGTGTTCAAGGACACGATGACCCCGACTCGCTGGAACTCTTACGTACCCTCCAAGGAAGACCTACAGAAGCTGCGCGACTCCGGGTTACCTCCGAGTTACTACGGCGTGGTGACTGGTGGTGACGGTGAGAACTGGGACGCCCTCATTAAGTTGGCCAAGGATAACTTCGAGGCTGACCAACGGGCAGCTGAGGCTGGTACTGGTGCAAAACTCGCTGCTGGTATCGTTGGCGCTGGTGTAGACCCGCTAAGTTATGTGCCGCTGGTCGGTGTGGCCGGGAAGGGACTCAAGGTGGTCAATAAGGCCCTGCGAGTAGGCGCACAGGCTGGAGCACTCAGCGTTGCCTCTGAGGGAATCCGTACGTCAGTAGCTGGTGGTGAAGCTCACTACGCTGATGCAGCCCTAGGTGGTCTACTGTTCGGCGCTGGCATGTCGGCCCTTAGTGACGCTGTGGCTGCTGGTATCCGTAAGGCACGTGGTGTTGAATCCGTGAACGAGTTCGCTGGTCCAGCACTCCGTATGGAAGCACGAGAGACTGCCATCAACACTGGTGGTCATGATACCTCGACACTGCCTCCAGAGAACTTCTCGTTCGAGCAGGACCACAGAGGCGTTCCGTTTGCCGACCACCCGACCGAAGAGGGAGCAGTGGTTCTGGCCAATGGTTCCATCCTGAGTGATACCAACCCGCTTAATCCAAGGACTCAACGTGACTTCGCAGAGATTGACCCAGAGCGTGCAGCTCCAGGTATCAAACTTGGTGGGTTCACTGAGATTGGCCTGAAGACCTTAGGGTCCAAGGATGCTGGTGTTCGTGCAATCGCTCAGGACCTCGTGCGCTCACCTACAGGTATGCAATCAGGGTCTAGTGGTAAGTTCGGTGCGACCGCTTCGGACATCCATGAGCGGCTCCATGCGACTGACCAACGGATGTATAACCAACTGTATGACGCGGTTGACCGTGCCATGAAGGACCCAGAGTTCTCCGTGGGCGAGCAGAAGATGTCTCGTAGAGCCATCCGTCAGGAAGTCTACAAGCGTGCGGCCTTGGCGATTGAGCGTCCAGAGTTACAGGCTGATTTGACCAAAGGTGAACGTGAGGTGATGGACCTGCTGAAAGAGCACTTCGACACCAAGCGTGAACTGATGGAACAGCCGGGTATCTTCGGCAACGCTAACGCAGTGAGCATCTTCCCCGGTAGTCGACACAAGGGTACATACGTGCCTAACGTGTACGACAGGGGTGCTAAGGAACTGATGATGCAGAAGCTGGGTGGACCTGAAGGACTCCAGCAGGCAATCGCTCAGAGCTGGCTTACCAGTTACCGAGTGCGTCCTGAGGTCAAGGCACGTGTCGACGAGTACCTGATGGAACTCAACGGCTACAAGTCGGTAGACCAAGTGACACCTGAGGTGGTCCAGAAGCACGCCATGGATAAGGCGTACGGCATCAGCCACACTGAGGACTTCACGGCATCCAGTGTCATTGATGACAACATCACAGGTCTGGTCGGTATCGAGAACAACTCGTTCCTTGAGGCCCGTAACATGTTCGACAGCGACCTCCCGGTTACCTTGCCGGATGGGTCAACCTTCAGTGTTAACGACCTGAGGGACTTCGACATGGCACGGATTATCCCAGCGTACGACCGTCGAGTTAACGGTGATATCTCCATCATGGGCGGTAGCGGTAAGACGACGCAGCAGCTCAAGGACGAAATCATGGCGTTAGACAAGCGGGCTGAACGTAAGGGACAGCTGAAGGGTGAAGTGGAAGCACTGAAGGATACCGTTAAGATTCTCACTGGACGTGCTCGTCGTAACCACGATACAGCCTTTGAGACCGCTATGCGCACCCTGAATGACCTAGCGTTCTTCGCTAAGAACTTCTACATGGGTCCTCAGAACCTCACCGAGATTGCGGGGATGTTGGCTAAAGGTAACGTTAAGGCGATGCTTCACGGTATCCCAACGTTGCGCGACCTAGCCACCAGAACCTCTCCGGTATCCGGTAGTGAACTCCGTGAACTCCATGGGGCGCTGTTCGGTAAGGAACTAGACCAGTTAATCCGTCCGGGACGCGAGGACATCGTACAGCGAATCCGCGAGGCTTCCGATACCAGTGGGGCCATGGCGTCAGTCATTGGTACCATTAAGTTCGGTACTCAGGAGCTGTCGGCTCGTTCTCCTTGGACCAAGATGTTGAACGGTACGGCCAACTACATTCTGGACACTGCCCGTCAGGGCGTGCTCGGTGATGTGGCTGGTGCGGCACTAGGCGGTAAAGGTTCCAAGTTTGGTAAAGAGAACTTCCTCAAAGCTGCCTCTATCAGTCCTGAGCAGTGGAAGGGAATTAAGCAACTCTTTGTCGACCACGCGACTCGTGACGCTAACGGTCAGTTCACCATCAAGGACAAGAAGGCTTTCAGTCAGGACCCGAGAGCGATGGACCTGTGGCGTCTCGCCGATAAGGTTGCCGATGAGACCATGCTGCGCCCTCACAAGGTGTCCCAGCAGGATTCCAAGGCATACGGTGCTGGTGTCAAGATGGCTATGCAGTTCAAGAACTTCACCATCAAATCACTCAACGCCAAGTTCATCCGGTCCTTCTACGAGGGCTACAAGAACAACCGCGCTATCGACATGGCGTTGACCCACGTGTTGTCTCTGGGTATCGCCGGGACTTACTTTGCGATGCAGGCCCACGTGAAGGCTTACGGCCTCCAAGAGTCCCAGCGTAAGGACTACCTGAAGAAAGCACTGAACCCGACCATGCTGGGCTACGCAGCGTTGACTCGAAGTTCCCACACTGGTGCCCCGCTGTCCATCGTTTCGATGATGGCTGGTGCCGCTGGGTTCCAAGATGCCAACATGCTGCGCTCCACCATCTTACCGAAGGAGGAACAGTTCCAGAAGAAAGACGGAGCGTCCAAAGGTAGAGCCGAGTCGAGCAACCTTGCGGGCAACTTGGGGTCTCAAGTCCCGGCTCTGGGTTACGTAGGGAACGTCATTGCGACCGCTAAGAACGCCTACGGTGTTGCTACAGCGCCCAACAAGCCGACTGAGCGTGACTACATGACTGGCCTGATGAACTCCACCAAGGAGCTTGTCCCGAACGACCCACTGACCCAACAGCTCATCATGAAAATCTATGAGGCCAACGGGGTCACCATCAAGCAACAGCCGAAGCCTAACTAA

Gene Ontology

Description Category Evidence (source)
GO:0000270 peptidoglycan metabolic process Biological process Inferred from Electronic Annotation (UniProt)
GO:0008933 peptidoglycan lytic transglycosylase activity Molecular function Inferred from Electronic Annotation (TreeGrafter)
GO:0016020 membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0016787 hydrolase activity Molecular function Inferred from Electronic Annotation (InterPro)
GO:0020002 host cell plasma membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044423 virion component Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)
GO:0099002 symbiont genome ejection through host cell envelope, short tail mechanism Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
4.2.2.n1 peptidoglycan lytic exotransglycosylase
aka exomuramidase; murein lyase F 		in the MurNAc residue
Lyases
Carbon-oxygen lyases
Acting on polysaccharides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04121

Tertiary structure

PDB ID: upi000b60c4fc_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A