Protein

UniProt accession
A0A223LEQ8 [UniProt]
Protein name
Baseplate central spike protein
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MLKGIDRFFTGVVEDRQDPYMLGRVRVRVHGIHPEQKVRADNYGLATEDLLWMSVGMPVTSASVSGVGQAPVGIVTGTHVYGIFLDEFYQNGLVLGTYPGIYPMMPDFNKGFSDPSREYPRYVGSDVNILARGGKEIKISPGQIVKENQIVPVVVEDQNLNRDVAQGADRTPNDEIYPNPDPDVTIEDMLRYDEGIRVSVYWDSEGYPTVGIGHLIVHEKTRNMTRINQLLSQQVGRPVNGRITEEECSMLFERDLSSVYSSISSNFKVGPVYSMLDDTRKMAIVNMTFQMGIGGVANFNMMLGYLALGQYDNAADAALDSLWARQTPSRARRVSEVIRNGNLVPYGGSQGSAPSLRTMRMFKAASVSTTAQAPSFTEPESPYSAVYPYNKVYESESGHIQEFDDTPGHERIRTYHRTGTFEEIHPDGTKVTKIIGDDFYIVKNDGNVHIGGKLKIVVDGDADIFVQGDSNSTISGNATQFVRGNVDERVEGNVNQYVTGNSSALVKGNLNADVDGNADIKVMGDCFNTIDGNYTLKIGGNFSTEVGGSRTDDVSGNWNRQSAQVSDVSQGTFSIDGSRINLG
Physico‐chemical
properties
protein length:583 AA
molecular weight:63957,00000 Da
isoelectric point:4,99520
aromaticity:0,08405
hydropathy:-0,38834

Domains

Domains [InterPro]
IPR002196
194–318
IPR002196 IPR009590 IPR010609
IPR023347
184–347
IPR023347
IPR052619
184–342
IPR052619
IPR046397
1–583
IPR046397
IPR001165
187–206
IPR001165
IPR023346
155–347
IPR023346
Protein sequence: A0A223LEQ8
1 583
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Aeromonas phage AS-gz
[NCBI] 		2026082 Straboviridae > Tulanevirus > Tulanevirus asgz
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ASU00767.1 [NCBI]
Genbank nucleotide accession
MF479730 [NCBI]
CDS location
range 152572 -> 154323
strand -
CDS
ATGTTAAAAGGTATTGATAGATTTTTTACTGGCGTCGTAGAAGATCGTCAGGATCCGTACATGTTAGGAAGGGTGAGAGTGCGTGTCCACGGTATTCACCCAGAACAAAAGGTTAGAGCAGACAACTATGGTTTAGCAACCGAGGATTTGCTGTGGATGTCAGTAGGCATGCCTGTAACATCAGCGTCAGTTTCGGGTGTAGGCCAGGCTCCAGTAGGCATCGTGACCGGTACTCACGTATACGGAATTTTCTTGGATGAATTTTATCAAAATGGCCTAGTTCTCGGGACATATCCAGGCATATATCCAATGATGCCTGATTTCAATAAAGGTTTTTCTGACCCATCAAGAGAATATCCTCGGTACGTCGGTTCAGATGTGAATATTTTGGCTAGAGGTGGAAAAGAAATAAAAATTTCACCAGGCCAAATTGTAAAAGAAAACCAAATTGTTCCAGTTGTCGTAGAAGATCAAAATCTCAACCGAGATGTTGCACAAGGTGCAGATAGAACACCCAATGACGAAATATACCCAAATCCAGATCCAGACGTAACAATAGAGGATATGCTGCGTTATGACGAAGGTATTCGTGTATCGGTTTATTGGGACAGTGAAGGATATCCAACTGTTGGAATAGGTCATTTGATAGTTCACGAAAAAACTAGAAATATGACAAGAATAAACCAATTGCTCAGTCAACAAGTAGGCAGGCCGGTTAATGGGAGAATAACCGAAGAAGAATGCTCTATGCTGTTTGAGCGTGATCTTTCCAGTGTCTATTCTAGCATATCAAGCAATTTCAAGGTTGGTCCGGTATATTCGATGCTAGATGATACTCGCAAAATGGCTATTGTCAATATGACGTTCCAAATGGGTATTGGTGGTGTAGCAAATTTCAATATGATGCTCGGATACTTGGCACTAGGCCAATACGATAACGCGGCTGATGCTGCTCTCGATTCGTTATGGGCTAGACAAACTCCATCACGAGCTCGTCGTGTGTCAGAAGTCATAAGAAATGGAAACTTGGTGCCGTATGGTGGGTCACAAGGATCTGCGCCGTCATTGCGGACGATGAGAATGTTCAAAGCGGCAAGTGTATCAACAACCGCCCAAGCTCCCTCGTTCACCGAGCCTGAATCACCTTACTCGGCTGTATATCCATATAACAAAGTGTATGAAAGTGAGTCTGGTCACATCCAGGAATTTGATGATACACCCGGGCATGAACGCATAAGAACATATCATCGGACGGGTACGTTTGAAGAAATACATCCTGATGGAACAAAAGTCACGAAAATTATTGGCGATGATTTCTACATTGTCAAGAACGATGGGAATGTTCATATCGGCGGAAAACTCAAGATCGTTGTCGACGGGGATGCTGATATTTTTGTTCAAGGCGATTCTAATAGCACAATATCTGGAAATGCTACCCAATTCGTTCGTGGTAATGTTGACGAGCGAGTAGAAGGTAATGTCAATCAGTATGTCACTGGAAATTCATCGGCGTTAGTAAAAGGAAATCTAAATGCAGATGTTGATGGAAACGCCGATATTAAAGTTATGGGTGACTGTTTTAACACGATTGATGGAAATTACACTCTAAAAATTGGAGGAAATTTTTCTACCGAAGTTGGAGGAAGTAGGACAGATGATGTTTCTGGTAATTGGAATAGACAATCGGCCCAAGTATCCGATGTTTCACAAGGAACATTCTCAATTGATGGTTCTAGAATAAACTTGGGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0098003 viral tail assembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0098025 virus tail, baseplate Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

PDB ID: upi000b9d6d77_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A