Protein

UniProt accession
H2BD99 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MAVVSEKTAGGRNVLAFLDMLAWSEGTSTIRGSDNGYNVVVGGGLFNGYADHPRLKVYLPRYKVYSTAAGRYQLLSRYWDAYRESLALKGGFTPSNQDLVALQQIKERRSLADIQAGRLADAVQKCSNIWASLPGAGYGQREHSLDDLTAHYLAAGGVLS
Physico‐chemical
properties
protein length:160 AA
molecular weight:17375,00000 Da
isoelectric point:9,01276
aromaticity:0,10000
hydropathy:-0,22250

Domains

Domains [InterPro]
IPR023346
9–157
IPR023346
IPR034691
1–160
IPR034691
Protein sequence: H2BD99
1 160
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage phi297
[NCBI] 		1129145 No lineage information
Host Pseudomonas aeruginosa
[NCBI] 		287 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AEX55866.1 [NCBI]
Genbank nucleotide accession
HQ711984 [NCBI]
CDS location
range 45936 -> 46418
strand +
CDS
ATGGCAGTCGTTTCCGAGAAAACCGCTGGAGGGAGGAACGTTCTTGCGTTCCTGGACATGCTTGCGTGGTCTGAGGGGACCAGCACGATCAGAGGTAGCGACAACGGCTACAACGTTGTTGTCGGTGGAGGGCTGTTCAATGGGTACGCTGATCACCCGCGCCTGAAGGTCTATCTGCCTCGCTACAAGGTTTATTCAACTGCGGCGGGCAGGTATCAGCTCCTTTCGAGGTACTGGGACGCCTACCGCGAAAGCCTGGCACTGAAAGGAGGTTTCACCCCATCTAACCAGGACCTGGTGGCGTTGCAGCAGATTAAGGAGCGACGCTCGCTCGCAGATATACAGGCTGGTCGCTTGGCGGATGCAGTGCAGAAGTGTTCCAACATCTGGGCCAGCCTGCCGGGGGCTGGTTACGGCCAACGCGAGCATTCTCTTGATGACCTGACCGCGCACTACCTTGCGGCGGGCGGAGTCCTTTCATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016829 lyase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
4.2.2.n2 peptidoglycan lytic endotransglycosylase MurNAc residue
Lyases
Carbon-oxygen lyases
Acting on polysaccharides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04109

Tertiary structure

PDB ID: upi000246a65d_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A