Protein

UniProt accession
H2BDD5 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MAVVSEKTAGGRNVLAFLDMLAWSEGTSTIRGSDNGYNVVVGGGLFNGYADHPRLKVYLPRYKVYSTAAGRYQLLSRYWDAYRESLALKGGFTPANQDLVALQQIKERRALADIQAGRLADAVQKCSNIWASLPGAGYGQREHSLDDLAAHYLAAGGVLS
Physico‐chemical
properties
protein length:160 AA
molecular weight:17313,00000 Da
isoelectric point:9,01276
aromaticity:0,10000
hydropathy:-0,17438

Domains

Domains [InterPro]
IPR034691
1–160
IPR034691
IPR023346
9–157
IPR023346
Protein sequence: H2BDD5
1 160
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Detrevirus PMG1
[NCBI] 		1129146 Detrevirus >
Host Pseudomonas aeruginosa
[NCBI] 		287 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AEX55902.1 [NCBI]
Genbank nucleotide accession
HQ711985 [NCBI]
CDS location
range 25549 -> 26031
strand +
CDS
ATGGCAGTCGTTTCCGAGAAAACCGCTGGAGGGAGGAACGTTCTTGCGTTCCTGGACATGCTTGCGTGGTCTGAGGGGACCAGCACGATCAGAGGTAGCGACAACGGCTACAACGTTGTTGTCGGTGGAGGGCTGTTCAATGGGTACGCTGATCACCCGCGCCTGAAGGTCTATCTGCCTCGGTACAAGGTTTATTCAACTGCGGCAGGCAGGTATCAGCTTCTCTCGAGGTATTGGGATGCCTATCGCGAAAGCCTGGCGCTGAAGGGCGGCTTCACCCCGGCTAACCAGGACCTGGTGGCGTTGCAGCAGATTAAGGAGCGCCGCGCGCTGGCAGATATACAGGCCGGTCGCTTGGCGGATGCCGTGCAGAAGTGCTCCAACATTTGGGCCAGCCTGCCGGGGGCTGGTTACGGCCAGCGTGAGCATTCTCTCGATGACCTGGCAGCGCACTATCTTGCAGCGGGCGGGGTGCTGTCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016829 lyase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
4.2.2.n2 peptidoglycan lytic endotransglycosylase MurNAc residue
Lyases
Carbon-oxygen lyases
Acting on polysaccharides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04109

Tertiary structure

PDB ID: upi000009b8fd_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A