Protein

UniProt accession
H2ELT8 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MPKFPQVGRLARSAVAVLSISAAGLGFIQHEEGTVNRAYLDSIGKPTICTGHTGPEVRLGLVYSDAQCAELLRTDANSAAAAVKRTIKVPLYQYEFDALVSFCFNVGNTNCTTSTMFKLINQGRYDEAGPQLLRWRYAGGKDCSVRANNCYGVYTRRHNEYALWQGQY
Physico‐chemical
properties
protein length:168 AA
molecular weight:18554,00000 Da
isoelectric point:8,92857
aromaticity:0,10714
hydropathy:-0,23036

Domains

Domains [InterPro]
IPR051018
10–164
IPR051018
IPR023347
6–167
IPR023347
IPR034690
8–167
IPR034690
IPR002196
30–160
IPR002196
IPR023346
14–167
IPR023346
Protein sequence: H2ELT8
1 168
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage Bf7
[NCBI] 		1100790 Autographiviridae > Bifseptvirus > Bifseptvirus Bf7
Host Pseudomonas tolaasii
[NCBI] 		29442 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AEX65840.1 [NCBI]
Genbank nucleotide accession
JN991020 [NCBI]
CDS location
range 139 -> 645
strand +
CDS
ATGCCTAAGTTCCCACAAGTAGGGCGCCTTGCGCGCTCTGCTGTGGCTGTCCTTAGTATCTCCGCAGCAGGCTTAGGCTTTATCCAACACGAAGAAGGAACCGTTAACCGGGCATACCTTGATTCGATTGGAAAGCCTACCATCTGCACCGGGCACACTGGCCCCGAGGTACGCTTAGGGTTAGTCTACAGCGACGCACAATGCGCTGAGCTGCTTCGCACGGACGCCAACTCGGCTGCCGCTGCTGTTAAGCGCACGATCAAAGTCCCGCTGTACCAGTACGAGTTCGACGCGCTCGTCTCGTTCTGCTTCAACGTCGGGAACACGAACTGCACCACAAGCACTATGTTCAAGCTGATCAACCAAGGTCGGTACGACGAGGCTGGGCCGCAACTCCTTCGCTGGCGTTATGCTGGTGGGAAGGACTGCTCCGTCCGGGCCAACAACTGCTACGGCGTTTACACCCGCCGTCACAACGAGTACGCACTATGGCAAGGACAATACTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi000247bd7a_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A