Protein

UniProt accession
K4I659 [UniProt]
Protein name
Baseplate central spike protein
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MDMINNNVEWFVGVVEDRMDPLKQGRVRVRVIGLHPFQKVQGPVSGMPTEDLPWMSVLQPITSASMSGIGGSVTGPVEGTHVYGHWLDKYRTNGLVMGTYGVNARVRPNTTEGFSDPTGQYPRYLGNDTNLLNQGGEAGFESIPNVIQDNNLDTAINPDDTDLSNIPEDNNPNYTIEAMLRRDEGLRLKVYWDTEGYPTIGIGHLIMRQRVRDMAQINKVLSNQVGREVKGNPGSITMDEASALFAKDLADMQRDIKTNSKVGPVYVKMNKSRQMALENMSFQMGVGGVANFTNMLKAMDEGRWKDAYNESRNSLWFQQTKGRASRVSMIILTGNMESYGVPVNPVQGKSVGAQLATVKASVNPSDPPIPSDSRILFKEPVSSYKGQYPYVHTMETESGHIQEFDDTPGYERYRLVHPTGTYEEVAPDGRRTRKTVNDLYDIANGDGNYLVSGDKKVNVGADETYYNMANRLHQIDGNNILFIRGDETKTVEGDGTLYVKGNIKIVVDGNADILVKGDAKTQVEGNHDYTVNGNVKWTVNGSVNMTVAGNWSETMSSMSSIAQGQYTIDGSRVDIGL
Physico‐chemical
properties
protein length:577 AA
molecular weight:63698,00000 Da
isoelectric point:5,31430
aromaticity:0,07452
hydropathy:-0,53674

Domains

Domains [InterPro]
IPR001165
177–196
IPR001165 IPR010609 IPR009590
IPR002196
183–311
IPR002196
IPR046397
3–576
IPR046397
IPR052619
173–338
IPR052619
IPR023347
178–342
IPR023347
IPR023346
131–341
IPR023346
Protein sequence: K4I659
1 577
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Salmonella phage STML-198
[NCBI] 		1204531 Straboviridae > Gelderlandvirus > Gelderlandvirus stml198
Host Salmonella
[NCBI] 		590 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae >

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AFU64090.1 [NCBI]
Genbank nucleotide accession
JX181825 [NCBI]
CDS location
range 109895 -> 111628
strand +
CDS
ATGGATATGATTAATAACAACGTCGAATGGTTTGTCGGCGTTGTAGAAGATAGAATGGACCCGTTAAAACAAGGACGAGTTCGTGTGAGAGTTATAGGTCTTCATCCATTCCAGAAAGTTCAAGGCCCTGTATCGGGAATGCCAACAGAAGACCTTCCATGGATGAGTGTTTTACAACCTATAACATCCGCATCTATGTCAGGAATAGGCGGTTCTGTCACTGGACCCGTCGAAGGAACTCATGTTTATGGTCATTGGTTGGACAAATATCGTACTAATGGTTTAGTGATGGGCACATACGGAGTAAATGCCAGAGTTAGACCAAACACTACAGAGGGTTTCTCTGATCCAACTGGCCAATATCCGCGTTACTTAGGTAATGATACTAACCTTTTGAACCAAGGTGGCGAAGCTGGATTTGAGTCAATCCCTAACGTTATTCAAGATAATAACCTTGATACGGCTATTAATCCTGACGACACAGATTTATCAAATATTCCAGAAGATAATAATCCAAATTATACTATAGAAGCTATGCTTCGCCGCGATGAAGGTCTTCGTTTGAAAGTATACTGGGACACTGAGGGATATCCGACTATCGGTATTGGGCATCTTATCATGAGACAAAGAGTCCGTGATATGGCACAAATTAATAAAGTGCTTTCAAATCAAGTTGGAAGAGAAGTTAAAGGAAATCCAGGTTCTATAACAATGGATGAAGCATCCGCATTATTTGCTAAAGACCTAGCTGATATGCAAAGAGATATAAAAACCAACTCAAAAGTCGGTCCAGTTTATGTCAAAATGAATAAATCGAGACAAATGGCTCTTGAAAATATGAGTTTTCAAATGGGCGTTGGTGGTGTAGCTAATTTCACTAATATGCTTAAAGCCATGGATGAAGGCCGTTGGAAAGATGCATATAACGAATCTCGAAACTCTTTATGGTTTCAGCAGACTAAAGGTCGAGCTTCTAGAGTATCTATGATTATTCTTACTGGTAATATGGAATCGTATGGTGTTCCTGTTAATCCGGTTCAAGGAAAATCCGTTGGTGCTCAATTAGCTACTGTTAAAGCTTCAGTTAATCCAAGCGACCCTCCTATACCAAGTGACAGCAGAATTCTTTTTAAAGAGCCTGTATCATCATATAAAGGACAATACCCTTATGTCCATACAATGGAAACTGAATCTGGTCACATTCAAGAATTTGATGATACTCCGGGTTATGAAAGATATCGTCTTGTTCATCCAACAGGGACATACGAAGAAGTAGCTCCTGATGGAAGAAGAACTAGAAAAACAGTAAATGATTTATACGATATTGCTAATGGTGATGGAAATTATTTAGTTTCCGGTGATAAAAAGGTAAACGTTGGTGCAGATGAAACATACTATAACATGGCCAACAGATTACATCAAATTGACGGAAATAATATTTTGTTTATCCGTGGAGATGAAACAAAAACTGTCGAAGGAGATGGAACACTTTACGTTAAAGGAAATATAAAGATAGTCGTTGACGGAAATGCTGATATCTTGGTTAAAGGAGATGCTAAAACTCAGGTTGAAGGAAATCACGATTATACAGTAAACGGAAACGTAAAATGGACTGTAAATGGTAGTGTTAATATGACAGTTGCTGGGAATTGGTCAGAAACTATGAGCTCAATGTCTTCTATAGCTCAGGGCCAATATACTATTGATGGCAGTCGTGTGGACATTGGTTTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0098003 viral tail assembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0098025 virus tail, baseplate Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

PDB ID: upi00028b8c14_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A