Protein

UniProt accession
L0ARW3 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MRNPLSKQMTALLTAFAMGGTGTAVVTQTDLLNQFLNEKEGNRLTAYLDSANPPIWTICRGVTRIDGKPVTKGMRLTERQCDLLNDKEAQKSLKWVRDNIPVKLNPVQQVGIASFCPYNIGPTKCKGSTFFKLLQKGDWKNACKQIPRWVFDGGKDCRIKSNNCSGQPIRREQEEYLCLYTLGEK
Physico‐chemical
properties
protein length:185 AA
molecular weight:20832,00000 Da
isoelectric point:9,40331
aromaticity:0,07568
hydropathy:-0,51189

Domains

Domains [InterPro]
IPR002196
38–173
IPR002196
IPR034690
11–181
IPR034690
IPR023347
6–181
IPR023347
IPR051018
9–180
IPR051018
IPR023346
29–181
IPR023346
Protein sequence: L0ARW3
1 185
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage JD001
[NCBI] 		1236000 Jedunavirus > Jedunavirus JD001
Host Klebsiella pneumoniae
[NCBI] 		573 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Klebsiella

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AFZ77614.1 [NCBI]
Genbank nucleotide accession
JX866719 [NCBI]
CDS location
range 41426 -> 41983
strand +
CDS
ATGAGAAATCCTCTAAGCAAACAAATGACTGCTCTTCTCACCGCATTTGCGATGGGTGGCACAGGTACCGCGGTAGTCACACAGACAGATCTGCTCAATCAGTTCCTGAACGAGAAGGAAGGGAACAGGTTGACAGCATATCTGGACAGTGCGAATCCTCCCATCTGGACCATCTGCCGGGGTGTGACACGCATCGATGGTAAACCGGTGACAAAGGGCATGCGGCTTACCGAAAGACAATGTGACCTTCTGAACGATAAAGAAGCACAGAAGTCACTCAAATGGGTGCGCGACAATATCCCGGTAAAACTGAACCCGGTGCAACAGGTTGGTATCGCGTCGTTCTGTCCGTATAACATTGGACCTACCAAATGCAAGGGGTCAACATTCTTTAAATTGCTGCAAAAAGGCGACTGGAAGAACGCGTGCAAACAGATTCCTCGTTGGGTATTTGACGGTGGTAAAGACTGTCGTATCAAAAGCAACAACTGTTCCGGACAGCCAATTCGTCGGGAGCAGGAAGAGTATTTGTGCCTGTATACATTGGGGGAGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi0002a8192d_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A