Protein

UniProt accession
M4W600 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MGRASEMRVSDNGTNFVKKWEGLYLRAYKDIVGVPTIGYGHTKNVSMGDRLAGEWEAHQLLKEDLDVHMIKARSQITSDLTQNQYDAITSFCFNLGANILTGTNLLQAINNSDWNEAGRIMLLYCNAGGKFVKGLYNRRVDEVALLKNGVQPPSPTPTPPDGDYDSSWFMDYNAKFTLDRKINLRTSPFADRDDNIIAILDSGDVITLNAFGNEESGFVWLRQVRSNGKYGYLASGNTENGKRVTVWGEFEDLD
Physico‐chemical
properties
protein length:254 AA
molecular weight:28423,00000 Da
isoelectric point:5,19226
aromaticity:0,10236
hydropathy:-0,46457

Domains

Domains [InterPro]
IPR023346
5–150
IPR023346 IPR003646
IPR023347
8–152
IPR023347
IPR034690
7–152
IPR034690
IPR002196
18–142
IPR002196
IPR051018
4–148
IPR051018
IPR033907
13–145
IPR033907
Protein sequence: M4W600
1 254
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage MG-B1
[NCBI] 		1309583 Salasmaviridae > Klosterneuburgvirus > Klosterneuburgvirus MGB1
Host Bacillus weihenstephanensis
[NCBI] 		86662 Bacteria > Firmicutes > Bacilli > Bacillales > Bacillaceae > Bacillus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AGI10624.1 [NCBI]
Genbank nucleotide accession
KC685370 [NCBI]
CDS location
range 22698 -> 23462
strand +
CDS
ATGGGTAGAGCAAGTGAAATGAGAGTATCTGATAATGGTACAAACTTTGTTAAAAAGTGGGAAGGTCTTTATTTAAGAGCGTATAAAGATATTGTTGGTGTTCCTACGATTGGTTACGGTCATACGAAAAATGTTAGTATGGGTGATAGACTTGCGGGAGAGTGGGAAGCACATCAATTATTGAAAGAAGATTTAGATGTTCATATGATTAAAGCTAGATCTCAAATAACTTCTGATTTAACACAAAATCAATATGACGCAATTACTAGTTTCTGTTTTAACTTAGGAGCTAATATTTTAACGGGTACAAATTTGTTACAAGCTATTAACAATAGTGACTGGAATGAAGCTGGAAGAATTATGTTGCTTTATTGTAATGCAGGTGGAAAGTTTGTAAAAGGTTTATACAATCGTAGAGTGGATGAAGTTGCTTTATTAAAGAATGGTGTCCAACCACCAAGTCCAACCCCTACCCCTCCAGATGGTGATTATGATTCTAGTTGGTTTATGGATTATAATGCTAAGTTTACATTGGATAGAAAAATTAATTTAAGAACTTCTCCATTTGCTGATAGAGATGATAATATTATTGCTATTTTGGATAGTGGAGATGTTATAACATTAAATGCTTTTGGAAATGAAGAAAGTGGTTTTGTTTGGTTAAGACAAGTTCGATCTAATGGTAAATATGGCTATCTTGCTAGTGGTAATACTGAAAATGGTAAACGTGTTACTGTTTGGGGTGAGTTTGAGGATTTAGATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi0002c50281_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A