Protein

UniProt accession

O64333 [UniProt]

Protein name

Tail tip assembly protein K

PhaLP type

endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence

MRQKTIDAIMAHAAAEYPRECCGVVAQKSRVERYFPCRNLSAEPTEHFHLSPEDYAAAEDWGTVVAIVHSHPDATTQPSELDKAQCDATLLPWHIVSWPEGDLRTIQPRGELPLLERPFVLGHFDCWGLVMSYFRQTHGIELHDYRVDYPWWENSYPDNFYQDCWYECGFREFDGPPQEGDLVIMQVQADKWNHAGILLEGNMLLHHLYGHLSQRVPYGGYWQERTMKIVRYKDVRGNEACRK

Physico‐chemical properties

protein length:	243 AA
molecular weight:	28325,00000 Da
isoelectric point:	5,48499
aromaticity:	0,12346
hydropathy:	-0,56296

Domains

Domains [InterPro]

IPR000064

96–233

IPR000064

IPR051929

1–210

IPR051929

IPR037518

1–120

IPR037518

IPR038765

112–234

IPR038765 IPR028090

IPR000064

117–231

IPR000064

IPR000555

1–124

IPR000555

Protein sequence: O64333

1 243

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR000064	96	233	PROSITE	Endopeptidase, NLPC/P60 domain
IPR051929	1	210	PANTHER	Viral Assembly and Modifier Protease
IPR037518	1	120	PROSITE	MPN domain
IPR038765	112	234	SUPFAM	Papain-like cysteine peptidase superfamily
IPR000064	117	231	PROSITE	Endopeptidase, NLPC/P60 domain
IPR028090	3	102	Pfam	JAB domain, prokaryotic
IPR000555	1	124	SMART	JAB1/MPN/MOV34 metalloenzyme domain

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage N15 (Bacteriophage N15) [NCBI]	1604876	Ravinvirus > Ravinvirus N15
Host	Escherichia coli [NCBI]	562	Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

Genbank protein accession

AAC19055.1 [NCBI]

Genbank nucleotide accession

AF064539 [NCBI]

CDS location

range 13981 -> 14712
strand +

CDS

ATGCGCCAGAAAACCATTGATGCCATCATGGCGCACGCCGCTGCGGAATATCCGCGCGAGTGCTGCGGCGTGGTAGCGCAGAAAAGCCGGGTTGAGCGCTATTTCCCCTGCCGCAACCTCTCAGCCGAGCCGACAGAGCATTTTCACCTTTCTCCTGAAGACTACGCAGCTGCCGAGGACTGGGGGACGGTGGTGGCCATTGTTCACAGCCACCCTGACGCCACGACACAGCCGAGCGAACTGGATAAAGCGCAATGTGATGCAACGCTGCTGCCCTGGCATATTGTGAGCTGGCCGGAGGGGGATTTACGCACTATTCAGCCGCGCGGGGAACTGCCGCTACTGGAGCGCCCGTTCGTGCTTGGCCACTTTGATTGCTGGGGGCTGGTCATGAGCTATTTCCGGCAGACCCACGGTATCGAACTCCATGATTACCGCGTCGACTATCCCTGGTGGGAGAACAGCTATCCGGACAACTTCTATCAGGACTGCTGGTACGAGTGCGGATTCAGGGAGTTTGACGGCCCGCCTCAGGAAGGGGACCTCGTCATCATGCAGGTGCAGGCGGATAAGTGGAACCATGCCGGAATATTGCTGGAAGGTAACATGCTGCTGCACCATCTTTACGGGCATCTGAGCCAGCGCGTGCCGTATGGTGGCTACTGGCAGGAGCGCACGATGAAAATCGTTCGATATAAAGATGTAAGGGGTAATGAAGCATGCAGGAAGTGA

Gene Ontology

	Description	Category	Evidence (source)
GO:0001897	symbiont-mediated cytolysis of host cell	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0006508	proteolysis	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0008234	cysteine-type peptidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0008235	metalloexopeptidase activity	Molecular function	Inferred from Electronic Annotation (InterPro)
GO:0008270	zinc ion binding	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0030430	host cell cytoplasm	Cellular component	Inferred from Electronic Annotation (UniProt)
GO:0098003	viral tail assembly	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID: upi000009b079_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A