Protein

UniProt accession
P07540 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MQISQAGINLIKSFEGLQLKAYKAVPTEKHYTIGYGHYGSDVSPRQVITAKQAEDMLRDDVQAFVDGVNKALKVSVTQNQFDALVSFAYNVGLGAFRSSSLLEYLNEGRTALAAAEFPRWNKSGGKVYQGLVNRRAQEQALFNSGTPKNVSRGTSSSKVTPKYKVKSGDNLTKIAKKHNTTVATLLKLNPSIKDPNMIRVGQTINVTGSGGKTHKVKSGDTLSKIAVDNKTTVSRLMSLNPEITNPNHIKVGQTIRLS
Physico‐chemical
properties
protein length:258 AA
molecular weight:28052,00000 Da
isoelectric point:10,02040
aromaticity:0,06202
hydropathy:-0,42209

Domains

Domains [InterPro]
IPR018392
212–257
IPR018392 IPR033907 IPR036779
IPR034690
1–145
IPR034690 IPR018392 IPR018392
IPR023346
1–145
IPR023346 IPR018392 IPR036779
IPR051018
2–144
IPR051018
IPR002196
12–138
IPR002196
IPR023347
2–151
IPR023347
Protein sequence: P07540
1 258
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage PZA (Bacteriophage PZA)
[NCBI] 		10757 Salasmaviridae > Salasvirus > Salasvirus PZA
Host Bacillus subtilis
[NCBI] 		1423 Bacteria > Firmicutes > Bacilli > Bacillales > Bacillaceae > Bacillus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAA88492.1 [NCBI]
Genbank nucleotide accession
M11813 [NCBI]
CDS location
range 15517 -> 16293
strand +
CDS
ATGCAAATTTCACAAGCAGGCATCAACTTAATTAAGAGTTTTGAAGGTTTACAACTGAAAGCCTATAAAGCTGTTCCAACTGAAAAGCATTACACAATTGGTTATGGGCATTACGGTTCTGATGTTTCACCTAGACAAGTTATCACTGCTAAACAGGCTGAAGACATGCTACGTGATGATGTACAGGCTTTTGTGGACGGTGTTAATAAAGCATTGAAAGTGTCTGTCACTCAGAATCAGTTTGATGCACTAGTCTCATTCGCTTATAACGTTGGGTTAGGGGCTTTCAGGTCTTCTTCTCTACTGGAATATTTGAACGAAGGTAGAACGGCTCTAGCGGCGGCTGAATTCCCTAGATGGAATAAGTCAGGAGGAAAGGTGTATCAAGGATTGGTTAACCGTAGAGCACAAGAGCAAGCCTTGTTTAATAGTGGAACACCTAAAAATGTTTCACGTGGAACATCGTCTTCTAAGGTGACACCTAAGTACAAGGTTAAAAGTGGTGACAACCTCACTAAAATCGCTAAAAAGCATAATACTACGGTTGCTACTCTGTTGAAACTCAATCCAAGTATTAAAGACCCTAACATGATTAGAGTTGGACAAACAATTAATGTTACGGGTAGCGGCGGCAAAACACATAAGGTGAAGAGTGGTGACACACTTAGCAAAATTGCGGTTGATAACAAAACAACTGTAAGTAGGCTTATGAGTCTCAACCCTGAAATTACTAATCCGAATCATATAAAAGTAGGTCAAACAATTAGACTAAGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000255 		HAMAP-Rule:MF_04110

Tertiary structure

PDB ID: upi000012ea4b_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A