Protein

UniProt accession
P51728 [UniProt]
Protein name
SAR-endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MSKKFGAMILCSAAAVAAAFFAQQKGLPTQQQNQVSPKAVSMIVNLEGCVRNPYKCPADVWTNGVGNTHNVDKTKILTIDEVATDLRRNIKEAENCINTYFNGEKMNQGQYDAMVSLAFNVGCGNIKTYYSKTQGKRVATTIYRAAQAENWILMCNRIEDFNKSGGRVLKGLQNRRAKEKALCLGE
Physico‐chemical
properties
protein length:186 AA
molecular weight:20553,00000 Da
isoelectric point:9,36095
aromaticity:0,07527
hydropathy:-0,36774

Domains

Domains [InterPro]
IPR002196
45–179
IPR002196
IPR023347
34–186
IPR023347
IPR043688
6–186
IPR043688
IPR051018
11–184
IPR051018
IPR034690
9–186
IPR034690
IPR023346
28–185
IPR023346
Protein sequence: P51728
1 186
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1)
[NCBI] 		1289570 Peduoviridae > Hpunavirus > Haemophilus phage HP1
Host Haemophilus influenzae
[NCBI] 		727

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAB09211.1 [NCBI]
Genbank nucleotide accession
U24159 [NCBI]
CDS location
range 20106 -> 20666
strand +
CDS
ATGAGTAAAAAATTTGGTGCAATGATTTTATGTTCAGCCGCAGCTGTCGCAGCCGCTTTTTTTGCCCAGCAGAAAGGCTTACCAACGCAACAACAAAATCAAGTTAGCCCAAAAGCGGTGTCAATGATTGTGAATTTAGAAGGTTGCGTGCGTAATCCGTACAAATGCCCTGCTGATGTGTGGACAAATGGGGTTGGAAACACCCATAACGTAGATAAAACCAAGATTTTAACCATTGATGAAGTAGCAACCGATTTACGTCGAAATATCAAAGAAGCGGAAAATTGCATTAACACCTATTTCAACGGCGAAAAGATGAATCAAGGGCAATATGACGCTATGGTGTCTTTAGCCTTTAACGTAGGCTGTGGCAACATCAAAACCTATTACAGCAAAACCCAAGGTAAACGTGTCGCAACCACGATTTATCGCGCAGCACAAGCGGAAAACTGGATATTAATGTGTAATCGTATTGAAGATTTTAACAAATCAGGCGGACGTGTGCTAAAAGGCTTACAAAACCGCAGAGCAAAAGAAAAAGCCCTATGTTTGGGGGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016020 membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0020002 host cell plasma membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000255 		HAMAP-Rule:MF_04136

Tertiary structure

PDB ID: upi000012ea40_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A