Protein

UniProt accession
P62693 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MKVSQNGLNLIKEFEGCRLTAYKPVPWEQMYTIGWGHYGVTAGTTWTQAQADSQLEIDINNKYAPMVDAYVKGKANQNEFDALVSLAYNCGNVFVADGWAPFSHAYCASMIPKYRNAGGQVLQGLVRRRQAELNLFNKPVSSNSNQNNQTGGMIKMYLIIGLDNSGKAKHWYVSDGVSVRHVRTIRMLENYQNKWAKLNLPVDTMFIAEIEAEFGRKIDMASGEVK
Physico‐chemical
properties
protein length:226 AA
molecular weight:25370,00000 Da
isoelectric point:8,85933
aromaticity:0,10619
hydropathy:-0,36327

Domains

Domains [InterPro]
IPR023346
1–140
IPR023346
IPR034690
1–139
IPR034690
IPR023347
2–149
IPR023347
IPR002196
12–132
IPR002196
IPR051018
2–137
IPR051018
IPR033907
7–137
IPR033907
Protein sequence: P62693
1 226
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactococcus phage phivML3 (Lactococcus bacteriophage phi-vML3)
[NCBI] 		10746 No lineage information
Host Lactococcus lactis
[NCBI] 		1358 Bacteria > Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
CAA34300.1 [NCBI]
Genbank nucleotide accession
X16178 [NCBI]
CDS location
range 505 -> 1185
strand +
CDS
ATAAAAGTATCACAAAACGGTTTGAACTTGATTAAAGAGTTTGAGGGTTGTAGGTTGACTGCTTATAAACCTGTACCGTGGGAACAAATGTACACTATCGGTTGGGGTCATTATGGAGTGACAGCAGGTACAACATGGACACAAGCTCAAGCAGATAGCCAGCTAGAGATTGACATCAATAATAAGTATGCACCTATGGTTGACGCTTACGTAAAAGGCAAAGCAAATCAAAATGAGTTTGACGCCTTAGTTTCATTGGCTTATAACTGTGGTAATGTTTTCGTTGCTGACGGTTGGGCGCCTTTCTCACATGCTTATTGTGCTTCAATGATACCGAAGTATCGTAATGCAGGCGGTCAAGTCTTACAAGGCTTAGTAAGACGCAGACAGGCAGAGCTTAACTTATTTAATAAACCAGTATCAAGTAATTCAAACCAAAACAATCAAACAGGAGGAATGATAAAAATGTACCTTATTATAGGACTAGATAATTCAGGTAAAGCTAAACATTGGTATGTTTCTGACGGTGTAAGTGTTCGTCATGTTCGTACAATTCGTATGTTGGAAAACTATCAAAACAAATGGGCTAAACTTAACTTGCCAGTTGATACAATGTTTATTGCAGAAATCGAAGCAGAGTTTGGACGTAAGATTGACATGGCTTCAGGAGAAGTGAAATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000255 		HAMAP-Rule:MF_04110

Tertiary structure

PDB ID: upi000012ea48_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A