Protein

UniProt accession
Q5G8R3 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MQISSNGITRLKREEGERLKAYPDSRGIPTIGVGHTGKVDGKPVVSGMTITAEKSSELLKEDLQWVEDAISSLVRVPLNQNQYDALCSLIFNIGKSAFAGSTVLRQLNLKNYQAAADAFLLWKKAGKDPDILLPRRRRERALFLS
Physico‐chemical
properties
protein length:145 AA
molecular weight:16070,00000 Da
isoelectric point:9,62437
aromaticity:0,06207
hydropathy:-0,31379

Domains

Domains [InterPro]
IPR033907
7–144
IPR033907
IPR034690
1–145
IPR034690
IPR002196
12–139
IPR002196
IPR023347
1–145
IPR023347
IPR023346
1–145
IPR023346
IPR051018
2–145
IPR051018
Protein sequence: Q5G8R3
1 145
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Enterobacteria phage ES18
[NCBI] 		101570 No lineage information
Host Salmonella enterica subsp. enterica serovar Typhimurium
[NCBI] 		90371 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Salmonella

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAW70547.1 [NCBI]
Genbank nucleotide accession
AY736146 [NCBI]
CDS location
range 44673 -> 45110
strand +
CDS
ATGCAAATCAGCAGTAACGGAATCACCAGATTAAAACGTGAAGAAGGCGAAAGACTAAAAGCCTATCCAGATAGCAGGGGGATACCAACCATTGGGGTTGGGCATACCGGAAAAGTGGATGGTAAACCTGTCGTATCAGGGATGACAATCACAGCCGAAAAATCTTCTGAGTTGCTCAAAGAGGATTTGCAGTGGGTTGAAGATGCGATAAGTAGTCTTGTTCGCGTCCCGCTAAATCAGAACCAGTATGATGCGCTATGTAGCCTTATATTCAATATAGGAAAATCAGCATTTGCCGGCTCTACCGTTCTACGCCAGTTGAATTTAAAGAATTACCAGGCAGCAGCAGATGCTTTCCTGTTATGGAAAAAAGCTGGTAAAGACCCTGATATTCTCCTTCCTCGGAGGCGGCGAGAAAGAGCGCTGTTCTTATCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi00004c984a_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A