Protein

UniProt accession
U3PDH1 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MKITKKIWCSVAAVISLITGGAIVGQEYVQPVGQVVIEGQALGELRISPKGLEMTGNAEGCRLDPYTCPSGLVTNGVGNTHGVPDNPVSLEQVAKDWVRNLQEAERCVESVERASGKPMTQGQFDAFTSFAFNTGCQRYKRNSNRTATQIYRLSLEGNYPQACAELKRWVYGGGVKQPGLIIRRNVEYERCMALD
Physico‐chemical
properties
protein length:195 AA
molecular weight:21374,00000 Da
isoelectric point:8,46491
aromaticity:0,07179
hydropathy:-0,30308

Domains

Domains [InterPro]
IPR023347
46–194
IPR023347
IPR051018
36–192
IPR051018
IPR002196
57–187
IPR002196
IPR034690
16–194
IPR034690
IPR023346
36–192
IPR023346
Protein sequence: U3PDH1
1 195
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage VPUSM 8
[NCBI] 		1341101 Peduoviridae > Longwoodvirus >
Host Vibrio cholerae O1
[NCBI] 		127906 Bacteria > Proteobacteria > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AGW43571.1 [NCBI]
Genbank nucleotide accession
KF361475 [NCBI]
CDS location
range 23040 -> 23627
strand +
CDS
ATGAAAATAACTAAAAAAATTTGGTGCTCAGTCGCCGCCGTGATCAGCCTTATCACGGGCGGGGCGATAGTCGGCCAAGAATACGTACAGCCAGTTGGTCAAGTGGTGATCGAAGGCCAAGCCCTTGGTGAACTACGCATCAGCCCAAAAGGGCTAGAAATGACAGGCAATGCAGAAGGGTGTCGTTTAGACCCGTACACCTGCCCATCCGGTTTAGTGACCAACGGCGTGGGCAACACTCACGGCGTGCCCGATAACCCCGTAAGCCTTGAGCAAGTCGCCAAAGATTGGGTGAGGAACCTGCAAGAAGCAGAACGCTGCGTGGAAAGTGTCGAACGCGCCTCAGGCAAACCCATGACACAAGGCCAGTTCGATGCGTTCACCTCCTTTGCCTTTAACACCGGGTGCCAGCGCTACAAACGCAACAGCAACCGCACAGCAACGCAGATTTATCGGTTAAGCCTTGAGGGGAACTACCCGCAAGCCTGTGCAGAGCTCAAACGCTGGGTGTATGGCGGCGGAGTAAAACAGCCGGGATTAATCATTCGACGGAATGTGGAATATGAACGCTGCATGGCACTGGATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi000009bc53_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A