Protein

UniProt accession
U3PFR1 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MHPIVKRAIALATVAGAGFIGGLAGDEGIRNVGHRDPGGRLDKPTACVGHTGPGVKEGVRYSDEQCAQWLAQDADNAAREAKRVIRPQLYAKLSQAERDSYSDFVFNKGLPNFQQSTMLRKLNAGDRVGACKEHRAWVYGRDKHGAKVKLPGLVKRAEKNAQECLAGVAGIRR
Physico‐chemical
properties
protein length:173 AA
molecular weight:18729,00000 Da
isoelectric point:9,78799
aromaticity:0,05780
hydropathy:-0,52312

Domains

Domains [InterPro]
IPR034690
7–167
IPR034690
IPR002196
27–159
IPR002196
IPR023347
2–168
IPR023347
IPR023346
19–168
IPR023346
IPR051018
9–167
IPR051018
Protein sequence: U3PFR1
1 173
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Burkholderia phage JG068
[NCBI] 		1401297 Autographiviridae > Mguuvirus > Mguuvirus JG068
Host Burkholderia cenocepacia
[NCBI] 		95486 Bacteria > Proteobacteria > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AGW43629.1 [NCBI]
Genbank nucleotide accession
KC853746 [NCBI]
CDS location
range 40232 -> 40753
strand +
CDS
ATGCACCCCATCGTCAAGCGAGCCATCGCGCTCGCCACGGTGGCTGGCGCGGGCTTCATCGGCGGGCTCGCCGGGGACGAGGGTATCCGGAACGTCGGGCACCGCGATCCCGGCGGGCGACTCGACAAGCCCACGGCATGCGTCGGCCACACTGGCCCCGGCGTCAAGGAAGGTGTCCGCTACAGCGATGAGCAATGCGCTCAGTGGCTGGCGCAGGACGCTGACAATGCCGCCCGCGAGGCCAAGAGAGTGATCCGTCCCCAATTATATGCGAAGCTGTCGCAGGCCGAGCGCGACTCGTACAGCGACTTCGTATTTAACAAGGGGCTTCCAAACTTCCAACAAAGCACCATGCTCCGTAAGCTGAACGCAGGGGATCGCGTAGGTGCTTGTAAGGAACACCGTGCTTGGGTCTACGGACGCGACAAGCATGGTGCTAAGGTCAAGCTGCCCGGCCTCGTTAAGCGCGCGGAGAAGAACGCGCAAGAGTGCCTCGCGGGCGTTGCTGGTATCCGGCGATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0030430 host cell cytoplasm Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID: upi0003b0c513_model

Method: AlphaFold3 Non-commercial

Resolution: –

Chain position: A